1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n
2. Number of hydrogen bond donors: 1<\/p>\n
3. Number of hydrogen bond acceptors: 1<\/p>\n
4. Number of rotatable chemical bonds: 0<\/p>\n
5. Number of tautomers: 3<\/p>\n
6. Topological molecule polar surface area 20.2<\/p>\n
7. Number of heavy atoms: 10<\/p>\n
8. Surface charge: 0<\/p>\n
9. Complexity: 120<\/p>\n
10. Number of isotope atoms: 0<\/p>\n
11. Determine the number of atomic stereocenters: 0<\/p>\n
12. Uncertain number of atomic stereocenters: 0<\/p>\n
13. Determine the number of chemical bond stereocenters: 0 <\/p>\n
14. Number of uncertain chemical bond stereocenters: 0<\/p>\n
15. Number of covalent bond units: 1<\/p>\n<\/p>\n
Properties and stability<\/h2>\n
1. Avoid contact with oxidants, acid anhydrides, and acid chlorides. <\/p>\n
2. It is highly toxic and highly irritating if swallowed or inhaled. Can be poisoned by absorption through the skin. The oral dose for rats is LD50820mg\/kg, and the oral dose for guinea pigs is LD501000mg\/kg. \u3000<\/span><\/p>\n<\/p>\n
Storage method<\/h2>\n
1. Store in a cool, ventilated warehouse. Keep away from fire and heat sources. Protect from direct sunlight. The packaging is sealed. They should be stored separately from oxidants, acid anhydrides and acid chlorides, and avoid mixed storage. Equipped with the appropriate variety and quantity of fire equipment. Suitable materials should be available in the storage area to contain spills. <\/p>\n
2. The wooden box outside the glass bottle is lined with padding or an iron drum. Store in a cool, ventilated warehouse; load and unload with care when handling to prevent damage to the container. <\/p>\n<\/p>\n
Synthesis method<\/h2>\n
Put 2,3,5,6-tetrachlorobenzene, solid alkali, and methanol into the autoclave, control the temperature at 135-152\u00b0C, and the pressure at 0.5-1.4MPa, and keep it for 14 hours. The reaction solution is cooled to 60\u00b0C, methanol is recovered by distillation, the residual liquid is released, cooled for crystallization, and filtered. Dissolve the crystals in water, heat to 70\u00b0C, add insurance powder, adjust pH = 9.2-9.6, add activated carbon, and decolorize at 95\u00b0C for half an hour. Filter, cool the filtrate to below 15\u00b0C, add hydrochloric acid to pH=2-3, filter out 2,4,5-trichlorophenol, and dry at 45\u00b0C to obtain the finished product. <\/p>\n<\/p>\n