{"id":48601,"date":"2024-05-11T17:43:11","date_gmt":"2024-05-11T09:43:11","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/48601"},"modified":"2024-05-11T17:43:11","modified_gmt":"2024-05-11T09:43:11","slug":"dl-lactide","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/48601","title":{"rendered":"DL-Lactide","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-48600\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/43adfd402213478595ce5ceff7e564be.gif\" width=\"198\" height=\"227\" alt=\"DL-lactide structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>02A9<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C6H8O4<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>144.13<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         3,6-dimethyl-1,4-dioxane-2,5-dione,<\/p>\n<p>                         lactide,<\/p>\n<p>                         3,6-Dimethyl-1,4-dioxane-2,5-dione,<\/p>\n<p>                         DL-Dilactide,<\/p>\n<p>                         Lactide<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>95-96-5<\/p>\n<p><b>MDL number:<\/b>MFCD00011685<\/p>\n<p><b>EINECS number:<\/b>202-468-3<\/p>\n<p><b>RTECS number:<\/b>JH1100000<\/p>\n<p><b>BRN number:<\/b>82121<\/p>\n<p><b>PubChem number:<\/b>24858300<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p><p>1. Characteristics: Undetermined<\/p>\n<p>2. Density (g\/mL, 25\u2103): Undetermined<\/p>\n<p>3. Relative vapor density (g\/mL, air=1  ): Undetermined<\/p>\n<p>4. Melting point (\u00baC): 116-119<\/p>\n<p>5. Boiling point (\u00baC, normal pressure): Undetermined<\/p>\n<p>6. Boiling point  (\u00baC, 8mmHg): 142 <\/p>\n<p>7. Refractive index: Undetermined<\/p>\n<p>8. Flash point (\u00baC): 180<\/p>\n<p>9. Specific rotation (  \u00ba): Undetermined<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC): Undetermined<\/p>\n<p>11. Vapor pressure (mmHg, \u00baC): Undetermined<\/p>\n<p>12. Saturated vapor pressure (kPa, \u00baC): Undetermined<\/p>\n<p>13. Heat of combustion (KJ\/mol): Undetermined<\/p>\n<p>14. Critical temperature (\u00baC): Undetermined  Determined<\/p>\n<p>15. Critical pressure (KPa): Undetermined<\/p>\n<p>16. Log value of oil-water (octanol\/water) partition coefficient: Undetermined<\/p>\n<p>17  . Explosion upper limit (%, V\/V): Undetermined<\/p>\n<p>18. Explosion lower limit (%, V\/V): Undetermined<\/p>\n<p>19. Solubility: Undetermined<\/p>\n<p>  p&gt;\n     <\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p><p>1. Other multiple dose toxicity: Oral TDLo for dogs: 35mg\/kg\/2W-I; Oral TDLo for dogs: 9100mg\/kg\/13W-I;<\/p>\n<\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None yet\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p><p>1. Molar refractive index: 31.20<\/p>\n<p>2. Molar volume (cm<sup>3<\/sup>\/mol): 125.0<\/p>\n<p>3. Isotonic specific volume (90.2K  ): 282.4<\/p>\n<p>4. Surface tension (dyne\/cm): 26.0<\/p>\n<p>5. Polarizability (10-24cm3): 12.37<\/p>\n<\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): 0.6<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 0<\/p>\n<p>3. Number of hydrogen bond acceptors: 4<\/p>\n<p>4. Number of rotatable chemical bonds: 0<\/p>\n<p>5. Number of tautomers: 3<\/p>\n<p>6. Topological molecule polar surface area 52.6<\/p>\n<p>7. Number of heavy atoms: 10<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 155<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 0<\/p>\n<p>12. Uncertain number of atomic stereocenters: 2<\/p>\n<p>13. Determine chemical bonds.Number of stereocenters: 0<\/p>\n<p>14. Number of uncertain chemical bond stereocenters: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None yet\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p>\n     None yet\n     <\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p><p>Using D,L-lactic acid as raw material, D,L-lactide is synthesized through dehydration cyclization in the presence of a catalyst.  The crude product was purified by recrystallization to prepare high-yield, high-purity D,L-lactide.  <\/p>\n<\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p><p>Mainly used in medicine.  <\/p>\n<\/p>\n<p>     extended-reading:<a href=\"https:\/\/www.bdmaee.net\/cyclohexylamine-product-series-cyclohexylamine-series-products\/\">https:\/\/www.bdmaee.net\/cyclohexylamine-product-series-cyclohexylamine-series-products\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44885\">https:\/\/www.newtopchem.com\/archives\/44885<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/149\">https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/149<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/38900\">https:\/\/www.newtopchem.com\/archives\/38900<\/a><\/br>extended-reading:<a href=\"https:\/\/www.morpholine.org\/category\/morpholine\/page\/10\/\">https:\/\/www.morpholine.org\/category\/morpholine\/page\/10\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/43979\">https:\/\/www.newtopchem.com\/archives\/43979<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/2-2-dimethylaminoethylmethylamino-ethanol-nnn-trimethylaminoethylethanolamine\/\">https:\/\/www.cyclohexylamine.net\/2-2-dimethylaminoethylmethylamino-ethanol-nnn-trimethylaminoethylethanolamine\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/582\">https:\/\/www.newtopchem.com\/archives\/582<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44903\">https:\/\/www.newtopchem.com\/archives\/44903<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/cas-136-53-8\/\">https:\/\/www.bdmaee.net\/cas-136-53-8\/<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 02A9 Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48600,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15244],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48601"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48601"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48601\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48600"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48601"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48601"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}