{"id":48846,"date":"2024-05-16T18:01:48","date_gmt":"2024-05-16T10:01:48","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/48846"},"modified":"2024-05-16T18:01:48","modified_gmt":"2024-05-16T10:01:48","slug":"nortriptyline","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/48846","title":{"rendered":"nortriptyline","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-48845\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/0709e699402444d0baaa8eb35c70fcd5.gif\" width=\"248\" height=\"227\" alt=\"Nortriptyline structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>01H8<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C19H21N<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>263.38<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         10,11-dihydro-5-(3-methylaminopropylidene)-5h-dibenzo[a,d][1,4]cycloheptene,<\/p>\n<p>                         3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>72-69-5<\/p>\n<p><b>MDL number:<\/b>None<\/p>\n<p><b>EINECS number:<\/b>200-788-8<\/p>\n<p><b>RTECS number:<\/b>None<\/p>\n<p><b>BRN number:<\/b>None<\/p>\n<p><b>PubChem ID:<\/b>None<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\"><SPAN><\/SPAN><SPAN><\/SPAN> <\/P>\n     <\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\"><SPAN>  Acute toxicity: Rat oral <SPAN>LD50<\/SPAN>: <SPAN>502 mg\/kg<\/SPAN>; Rat intravenous <SPAN>LD50  <\/SPAN>: <SPAN>22 mg\/kg<\/SPAN>; <SPAN><\/SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN> <\/SPAN><\/SPAN><SPAN>Mouse oral administration <SPAN>LD50<\/SPAN>: <SPAN>370 mg\/kg<\/SPAN>; Mouse abdominal cavity <SPAN>LD50<\/SPAN>: <SPAN>70 mg\/kg<\/SPAN>; <SPAN>Mouse Vein<SPAN>LD50<\/SPAN>\uff1a<SPAN>17 mg\/kg<\/SPAN>; <\/SPAN><SPAN><\/SPAN><\/SPAN><\/P>\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\">  <SPAN><SPAN> 1. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Molar refractive index:<\/SPAN><SPAN>86.76<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>2. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Molar volume (<\/SPAN><SPAN>m<SUP>3<\/SUP>\/mol<\/SPAN><SPAN>\uff09\uff1a<\/SPAN><SPAN>242.8<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>3. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>isotonic specific volume (<\/SPAN><SPAN>90.2K<\/SPAN><SPAN>):<\/SPAN><SPAN>636.9<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>4. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Surface Tension (<\/SPAN><SPAN>dyne\/cm<\/SPAN><SPAN>):<\/SPAN><SPAN>47.3<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>5. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Polarizability<\/SPAN><SPAN>\uff08<\/SPAN><SPAN>10<SUP>-24<\/SUP>cm<SUP>3<\/SUP><\/SPAN><SPAN>):<\/SPAN><SPAN>34.39<\/SPAN><\/P>\n     <\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 1<\/p>\n<p>3. Number of hydrogen bond acceptors: 1<\/p>\n<p>4. Number of rotatable chemical bonds: 3<\/p>\n<p>5. Number of tautomers: none<\/p>\n<p>6. Topological molecule polar surface area 12<\/p>\n<p>7. Number of heavy atoms: 20<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 307<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 0<\/p>\n<p>12. The number of uncertain stereocenters of atoms: 0<\/p>\n<p>13. The number of determined stereocenters of chemical bonds: 0<\/p>\n<p>14. The number of uncertain stereocenters of chemical bonds: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p>\n     None\n     <\/p>\n<p>     extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/1031\">https:\/\/www.newtopchem.com\/archives\/1031<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/jeffcat-zr-70-catalyst-cas1704-62-7-huntsman\/\">https:\/\/www.bdmaee.net\/jeffcat-zr-70-catalyst-cas1704-62-7-huntsman\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/cas-90-72-2\/\">https:\/\/www.bdmaee.net\/cas-90-72-2\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/niax-b-18-tertiary-amine-catalyst-momentive\/\">https:\/\/www.bdmaee.net\/niax-b-18-tertiary-amine-catalyst-momentive\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/low-odor-catalyst-polycat-9-tertiary-amine-catalyst-polycat-9\/\">https:\/\/www.cyclohexylamine.net\/low-odor-catalyst-polycat-9-tertiary-amine-catalyst-polycat-9\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/strong-gel-catalyst\/\">https:\/\/www.bdmaee.net\/strong-gel-catalyst\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/dabco-nem-niax-nem-jeffcat-nem\/\">https:\/\/www.cyclohexylamine.net\/dabco-nem-niax-nem-jeffcat-nem\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.morpholine.org\/dimethomorph\/\">https:\/\/www.morpholine.org\/dimethomorph\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.morpholine.org\/category\/morpholine\/page\/5387\/\">https:\/\/www.morpholine.org\/category\/morpholine\/page\/5387\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/39796\">https:\/\/www.newtopchem.com\/archives\/39796<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 01H8 Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":48845,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15322],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48846"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=48846"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/48846\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/48845"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=48846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=48846"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=48846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}