<\/p>\n
Structural formula<\/p>\n
L(+)-aminosuccinic acid,<\/p>\n
L-aspartic acid,<\/p>\n
(S)-(+)-Aminosuccinic acid,<\/p>\n
(S)-Aspartic acid,<\/p>\n
biochemical reagents,<\/p>\n
Intermediates<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
CAS number:<\/b>56-84-8<\/p>\n
MDL number:<\/b>MFCD00002616<\/p>\n
EINECS number:<\/b>200-291-6<\/p>\n
RTECS number:<\/b>CI9098500<\/p>\n
BRN number:<\/b>1723530<\/p>\n
PubChem ID:<\/b>None<\/p>\nPhysical property data<\/h2>\n
1. Properties: Colorless orthorhombic leaf-shaped or rod-shaped crystals or crystalline powder, odorless. Often left-handed optical rotation. <\/p>\n
2. Density (g\/mL, 25\/4\u2103): (d12.5\/4) 1.514<\/p>\n
3. Relative vapor density (g\/mL, air=1) : Undetermined<\/p>\n
4. Melting point (\u00baC): 270-271<\/p>\n
5. Boiling point (\u00baC, normal pressure): Undetermined<\/p>\n
6. Boiling point ( \u00baC, 5.2kPa): Not determined<\/p>\n
7. Refractive index: Not determined<\/p>\n
8. Flash point (\u00baC): Not determined<\/p>\n
9. Specific optical rotation Degree (\u00ba): [a]20\/D+25\u00b0 (c=1.97, in 6mol\/L hydrochloric acid). <\/p>\n
10. Autoignition point or ignition temperature (\u00baC): Undetermined<\/p>\n
11. Vapor pressure (kPa, 25\u00baC): Undetermined<\/p>\n
12. Saturation Vapor pressure (kPa, 60\u00baC): Undetermined<\/p>\n
13. Heat of combustion (KJ\/mol): Undetermined<\/p>\n
14. Critical temperature (\u00baC): Undetermined<\/p>\n
15. Critical pressure (KPa): Undetermined<\/p>\n
16. Log value of oil-water (octanol\/water) partition coefficient: Undetermined<\/p>\n
17. Explosion upper limit (% , V\/V): Undetermined<\/p>\n
18. Lower explosion limit (%, V\/V): Undetermined<\/p>\n
19. Solubility: soluble in hot water, acid, alkali and Salt solution, insoluble in ethanol and ether. <\/p>\n<\/p>\n
1. Acute toxicity: mouse abdominal LC50: 6mg\/kg<\/p>\n
2. Other multiple dose toxicity: rat oral TDLo: 25079mg\/kg\/7D-C<\/p>\n
3. Mutagenicity: sister chromatids exchangeTEST system: human lymphocytes: 10mg\/L<\/p>\n<\/p>\n
\n None\n <\/p>\n
1. Molar refractive index: 27.20<\/p>\n
2. Molar volume (cm3<\/sup>\/mol): 87.8<\/p>\n3. Isotonic specific volume (90.2K ): 261.3<\/p>\n4. Surface tension (dyne\/cm): 78.2<\/p>\n5. Polarizability (10-24<\/sup>cm3<\/sup>): 10.78<\/p>\n<\/p>\nCompute chemical data<\/h2>\n1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n2. Number of hydrogen bond donors: 3<\/p>\n3. Number of hydrogen bond acceptors: 5<\/p>\n4. Number of rotatable chemical bonds: 3<\/p>\n5. Number of tautomers: none<\/p>\n6. Topological molecule polar surface area 101<\/p>\n7. Number of heavy atoms: 9<\/p>\n8. Surface charge: 0<\/p>\n9. Complexity: 133<\/p>\n10. Number of isotope atoms: 0<\/p>\n11. Determine the number of atomic stereocenters: 1<\/p>\n12. Uncertain number of atomic stereocenters: 0<\/p>\n13. Determine the number of chemical bond stereocenters: 0 <\/p>\n14. Number of uncertain chemical bond stereocenters: 0<\/p>\n15. Number of covalent bond units: 1<\/p>\n<\/p>\nProperties and stability<\/h2>\n1. Stable properties under normal temperature and pressure. <\/p>\n2. It is a natural product and non-toxic. <\/p>\n3. Exist in tobacco leaves and smoke. <\/p>\n<\/p>\nStorage method<\/h2>\nSeal and store in a dry place. <\/p>\n<\/p>\nSynthesis method<\/h2>\n1. The preparation methods of L-aspartic acid include synthesis method and fermentation method. 1. The synthesis method mainly uses maleic acid or fumaric acid or their esters as raw materials, which are treated with ammonia under pressure and then hydrolyzed. It is relatively easy to synthesize racemic aspartic acid, but so far there is no ideal method to separate the racemate. 2. In the fermentation method, fumaric acid and ammonia are added under the action of enzymes to obtain products with high yields. This method only generates the left-handed form with high yield, so it is the main method for industrial production. <\/p>\n2. Obtained from fumaric acid and ammonia under the action of aspartase of Pseudomonas clover or Brevibacterium ammoniagenes. <\/p>\n3. Use maleic acid, fumaric acid or their esters as raw materials, and add ammonia under the action of enzymes. The reaction is as follows:<\/p>\n<\/p>\n4. Tobacco: BU, 22; FC, 21. <\/p>\n<\/p>\nPurpose<\/h2>\n1. Biochemical and medical clinical research. It can be used as an ammonia detoxifier, liver function promoter, fatigue recovery agent and other pharmaceuticals. It can be used to make L-sodium aspartate food additives and additives for various refreshing drinks. It can also be used as biochemical reagents, culture media and organic synthesis intermediates. <\/p>\n2. Can be used as biochemical reagents, culture media and organic synthesis intermediates. In medicine, it is used as a component of heart disease drugs, liver function promoters, ammonia detoxifiers, fatigue relievers and amino acid infusions. It is also used as a preservative in the food industry. <\/p>\n3. Nutritional supplements. Add to various refreshing drinks. It is used medicinally as an ammonia detoxifier and liver function promoter. Used as nutritional additive in cosmetics. <\/p>\n4. L-aspartic acid is often used as a chiral substrate in diastereomeric alkylation reactions, and can be used as a chiral source to synthesize other chiral compounds. <\/p>\nDiastereoselective alkylation<\/strong> L-aspartate ester can be used in \u03b1<\/em>– and \u03b2<\/em>– Alkylation occurs (formula 1) [2]<\/sup>, among which the \u03b2<\/em>-alkylation reaction is the most widely used. During the \u03b2<\/em>-alkylation reaction, the amino acid moiety has an important influence on the diastereoselectivity of the reaction. At the same time, \u03b2<\/em>-dicarbonyl compounds can also be prepared through \u03b2<\/em>-alkylation of cyclic derivatives of L-aspartic acid [3]<\/sup>. <\/p>\n<\/p>\n<\/strong><\/p>\nSynthesis of Chiral Compounds<\/strong> Using L-aspartic acid as the chiral source, a series of chiral compounds can be synthesized, such as using copper iodide After the action of sodium borohydride, etc., a multifunctional oxygen nitrogen heterocyclic compound (formula 2) can be obtained, which can further generate a quinoline compound [4]<\/sup>. <\/p>\n<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
3. Isotonic specific volume (90.2K ): 261.3<\/p>\n
4. Surface tension (dyne\/cm): 78.2<\/p>\n
5. Polarizability (10-24<\/sup>cm3<\/sup>): 10.78<\/p>\n<\/p>\nCompute chemical data<\/h2>\n1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n2. Number of hydrogen bond donors: 3<\/p>\n3. Number of hydrogen bond acceptors: 5<\/p>\n4. Number of rotatable chemical bonds: 3<\/p>\n5. Number of tautomers: none<\/p>\n6. Topological molecule polar surface area 101<\/p>\n7. Number of heavy atoms: 9<\/p>\n8. Surface charge: 0<\/p>\n9. Complexity: 133<\/p>\n10. Number of isotope atoms: 0<\/p>\n11. Determine the number of atomic stereocenters: 1<\/p>\n12. Uncertain number of atomic stereocenters: 0<\/p>\n13. Determine the number of chemical bond stereocenters: 0 <\/p>\n14. Number of uncertain chemical bond stereocenters: 0<\/p>\n15. Number of covalent bond units: 1<\/p>\n<\/p>\nProperties and stability<\/h2>\n1. Stable properties under normal temperature and pressure. <\/p>\n2. It is a natural product and non-toxic. <\/p>\n3. Exist in tobacco leaves and smoke. <\/p>\n<\/p>\nStorage method<\/h2>\nSeal and store in a dry place. <\/p>\n<\/p>\nSynthesis method<\/h2>\n1. The preparation methods of L-aspartic acid include synthesis method and fermentation method. 1. The synthesis method mainly uses maleic acid or fumaric acid or their esters as raw materials, which are treated with ammonia under pressure and then hydrolyzed. It is relatively easy to synthesize racemic aspartic acid, but so far there is no ideal method to separate the racemate. 2. In the fermentation method, fumaric acid and ammonia are added under the action of enzymes to obtain products with high yields. This method only generates the left-handed form with high yield, so it is the main method for industrial production. <\/p>\n2. Obtained from fumaric acid and ammonia under the action of aspartase of Pseudomonas clover or Brevibacterium ammoniagenes. <\/p>\n3. Use maleic acid, fumaric acid or their esters as raw materials, and add ammonia under the action of enzymes. The reaction is as follows:<\/p>\n<\/p>\n4. Tobacco: BU, 22; FC, 21. <\/p>\n<\/p>\nPurpose<\/h2>\n1. Biochemical and medical clinical research. It can be used as an ammonia detoxifier, liver function promoter, fatigue recovery agent and other pharmaceuticals. It can be used to make L-sodium aspartate food additives and additives for various refreshing drinks. It can also be used as biochemical reagents, culture media and organic synthesis intermediates. <\/p>\n2. Can be used as biochemical reagents, culture media and organic synthesis intermediates. In medicine, it is used as a component of heart disease drugs, liver function promoters, ammonia detoxifiers, fatigue relievers and amino acid infusions. It is also used as a preservative in the food industry. <\/p>\n3. Nutritional supplements. Add to various refreshing drinks. It is used medicinally as an ammonia detoxifier and liver function promoter. Used as nutritional additive in cosmetics. <\/p>\n4. L-aspartic acid is often used as a chiral substrate in diastereomeric alkylation reactions, and can be used as a chiral source to synthesize other chiral compounds. <\/p>\nDiastereoselective alkylation<\/strong> L-aspartate ester can be used in \u03b1<\/em>– and \u03b2<\/em>– Alkylation occurs (formula 1) [2]<\/sup>, among which the \u03b2<\/em>-alkylation reaction is the most widely used. During the \u03b2<\/em>-alkylation reaction, the amino acid moiety has an important influence on the diastereoselectivity of the reaction. At the same time, \u03b2<\/em>-dicarbonyl compounds can also be prepared through \u03b2<\/em>-alkylation of cyclic derivatives of L-aspartic acid [3]<\/sup>. <\/p>\n<\/p>\n<\/strong><\/p>\nSynthesis of Chiral Compounds<\/strong> Using L-aspartic acid as the chiral source, a series of chiral compounds can be synthesized, such as using copper iodide After the action of sodium borohydride, etc., a multifunctional oxygen nitrogen heterocyclic compound (formula 2) can be obtained, which can further generate a quinoline compound [4]<\/sup>. <\/p>\n<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n
2. Number of hydrogen bond donors: 3<\/p>\n
3. Number of hydrogen bond acceptors: 5<\/p>\n
4. Number of rotatable chemical bonds: 3<\/p>\n
5. Number of tautomers: none<\/p>\n
6. Topological molecule polar surface area 101<\/p>\n
7. Number of heavy atoms: 9<\/p>\n
8. Surface charge: 0<\/p>\n
9. Complexity: 133<\/p>\n
10. Number of isotope atoms: 0<\/p>\n
11. Determine the number of atomic stereocenters: 1<\/p>\n
12. Uncertain number of atomic stereocenters: 0<\/p>\n
13. Determine the number of chemical bond stereocenters: 0 <\/p>\n
14. Number of uncertain chemical bond stereocenters: 0<\/p>\n
15. Number of covalent bond units: 1<\/p>\n<\/p>\n
1. Stable properties under normal temperature and pressure. <\/p>\n
2. It is a natural product and non-toxic. <\/p>\n
3. Exist in tobacco leaves and smoke. <\/p>\n<\/p>\n
Seal and store in a dry place. <\/p>\n<\/p>\n
1. The preparation methods of L-aspartic acid include synthesis method and fermentation method. 1. The synthesis method mainly uses maleic acid or fumaric acid or their esters as raw materials, which are treated with ammonia under pressure and then hydrolyzed. It is relatively easy to synthesize racemic aspartic acid, but so far there is no ideal method to separate the racemate. 2. In the fermentation method, fumaric acid and ammonia are added under the action of enzymes to obtain products with high yields. This method only generates the left-handed form with high yield, so it is the main method for industrial production. <\/p>\n
2. Obtained from fumaric acid and ammonia under the action of aspartase of Pseudomonas clover or Brevibacterium ammoniagenes. <\/p>\n
3. Use maleic acid, fumaric acid or their esters as raw materials, and add ammonia under the action of enzymes. The reaction is as follows:<\/p>\n
4. Tobacco: BU, 22; FC, 21. <\/p>\n<\/p>\n
1. Biochemical and medical clinical research. It can be used as an ammonia detoxifier, liver function promoter, fatigue recovery agent and other pharmaceuticals. It can be used to make L-sodium aspartate food additives and additives for various refreshing drinks. It can also be used as biochemical reagents, culture media and organic synthesis intermediates. <\/p>\n
2. Can be used as biochemical reagents, culture media and organic synthesis intermediates. In medicine, it is used as a component of heart disease drugs, liver function promoters, ammonia detoxifiers, fatigue relievers and amino acid infusions. It is also used as a preservative in the food industry. <\/p>\n
3. Nutritional supplements. Add to various refreshing drinks. It is used medicinally as an ammonia detoxifier and liver function promoter. Used as nutritional additive in cosmetics. <\/p>\n
4. L-aspartic acid is often used as a chiral substrate in diastereomeric alkylation reactions, and can be used as a chiral source to synthesize other chiral compounds. <\/p>\n
Diastereoselective alkylation<\/strong> L-aspartate ester can be used in \u03b1<\/em>– and \u03b2<\/em>– Alkylation occurs (formula 1) [2]<\/sup>, among which the \u03b2<\/em>-alkylation reaction is the most widely used. During the \u03b2<\/em>-alkylation reaction, the amino acid moiety has an important influence on the diastereoselectivity of the reaction. At the same time, \u03b2<\/em>-dicarbonyl compounds can also be prepared through \u03b2<\/em>-alkylation of cyclic derivatives of L-aspartic acid [3]<\/sup>. <\/p>\n<\/p>\n<\/strong><\/p>\nSynthesis of Chiral Compounds<\/strong> Using L-aspartic acid as the chiral source, a series of chiral compounds can be synthesized, such as using copper iodide After the action of sodium borohydride, etc., a multifunctional oxygen nitrogen heterocyclic compound (formula 2) can be obtained, which can further generate a quinoline compound [4]<\/sup>. <\/p>\n<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/strong><\/p>\nSynthesis of Chiral Compounds<\/strong> Using L-aspartic acid as the chiral source, a series of chiral compounds can be synthesized, such as using copper iodide After the action of sodium borohydride, etc., a multifunctional oxygen nitrogen heterocyclic compound (formula 2) can be obtained, which can further generate a quinoline compound [4]<\/sup>. <\/p>\n<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Synthesis of Chiral Compounds<\/strong> Using L-aspartic acid as the chiral source, a series of chiral compounds can be synthesized, such as using copper iodide After the action of sodium borohydride, etc., a multifunctional oxygen nitrogen heterocyclic compound (formula 2) can be obtained, which can further generate a quinoline compound [4]<\/sup>. <\/p>\n<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/sup><\/p>\n<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/sup><\/strong><\/p>\nFormation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Formation of amide bond<\/strong> L-aspartic acid, as an amino acid, is the same as other amino acids Amide compounds (formula 3)[5]<\/sup> can also be generated. <\/p>\n<\/p>\nAt the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
At the same time, you can also use L- Aspartic acid is used as the parent to realize the synthesis of cyclic lactam. For example, the synthesis of six-membered ring lactam (formula 4)[6]<\/sup>. The alkoxy group is also present in the product and therefore serves as an additional reaction site for further derivatization. <\/p>\n<\/p>\n\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u03b2 <\/em>Synthesis of amino acids (or amino acid esters)<\/strong> L-aspartic acid can generate \u03b2<\/em>-amino acids or amino acid esters ( Formula 5)[10]<\/sup>, this reaction realizes the conversion from natural amino acids to unnatural amino acids. <\/p>\n<\/p>\n<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/strong><\/p>\nIn addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
In addition, the L-aspartic acid molecule contains two carboxyl groups and one amino group, so it can be used as a multidentate ligand to coordinate with metal ions[7~9] <\/sup>Or form lactone compounds themselves[10,11]<\/sup>. <\/p>\n<\/p>\n extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
extended-reading:https:\/\/www.bdmaee.net\/organic-mercury-replacement-catalyst-nt-cat-e-at\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/206<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/spraying-composite-amine-catalyst-NT-CAT-PT1003-PT1003.pdf<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/100<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/823<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44108<\/a><\/br>extended-reading:https:\/\/www.bdmaee.net\/cas-6711-48-4\/<\/a><\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/k-15-catalyst-potassium-isooctanoate\/<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/767<\/a><\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44131<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Structural formula Business number 017Y Molecular formu…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49253,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[5846],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49254"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49253"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49254"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
![\"L-aspartic](\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/22ecf73358b747819b701dc6de405eab.gif\")
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